Over the many Givi boxes that I and friends have bought, only one (belonging to a friend and fitted to a 1970 CB750) gave problems, and quite serious problems at that.
On occasion, it seems particularly when it was filled with clothing and a helmet, he simply could not open it to retrieve his gear and ride home!
It was repaired by Givi under warranty, however it never was totally reliable and in the end he replaced it with another.